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KMID : 0922220080080020077
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Journal of the Korean Musculoskeletal Transplantation Society
2008 Volume.8 No. 2 p.77 ~ p.83
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Results of Transplantation of Deep Frozen Allograft Stored in Surgical Bone Bank
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Cho Yoon-Je
Kim Kang-Il
Chun Young-Soo
Rhyu Kee-Hyung
Roh Jun-Ha
Kim Man-Ho
Kang Chang-Min
Yoo Myung-Chul
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Abstract
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Purpose: To analyze the clinical, radiological results and complications after transplantation of deep frozen allograft stored in surgical bone bank.
Materials and methods: Between Feb. 1998 to Sep. 2005, candidates were 257 deep frozen allograft stored in surgical bone bank. All of the procured bones were resected femoral heads during primary total hip arthroplasty(THA). The causes of primary THA were osteonecrosis of the femoral head in 122 cases(47.5%), femur neck fracture in 73 cases(28.4%), primary and secondary osteoarthritis in 50 cases(19.5%), and intertrochanteric fracture in 12 cases(4.6%). The average age of donors was 59.9(range, 18-86) years old and 148 were female and 109 were male. After bone graft, we evaluated clinical and radiological outcome and blood analysis including liver function test, serologic study and CBC/DC, ESR, CRP.
Results: 140 operations were performed using allografts and average 1.8(range, 1-5) allografts were used at each operation. Most were used in revision surgeries of the prosthetic joint on bone defect area. In the hip joints, 209 allografts were used in 100 cases (71.4%) and average 2.1(range, 1-5) allografts were used at each operation and in the knee joint, 48 allografts were used in 40 cases (28.6%) and average 1.2(range, 1-3) allografts were used at each operation. Resorption of the allografts was observed in 12 cases (4.7%) and 3 cases were gradually progressed. No infection and no hematogenous disease transmission were occurred.
Conclusion: Deep frozen allograft was an effective method for mechanical stability with filling up the bone defect in orthopedic surgery and for prevention of the infection and hematogenous spreading of the disease, meticulous evaluation and management of donor’s medical conditions must be considered.
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KEYWORD
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Deep frozen allograft, Bone graft, Bone bank
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